Beta-Lactams

Villadose, Italy

Located near Venice, our Villadose facility is a dedicated European center of excellence for Beta-Lactam API development and manufacturing.

Backed by decades of expertise and advanced production technologies, the site delivers high-quality Beta-Lactam APIs to customers worldwide.

Through our integrated manufacturing network, we support projects from development to commercial supply. In addition, through our Santiago facility, sterile Beta-Lactam products are available from API through to finished dosage forms, offering customers a seamless end-to-end solution.

Why Fresenius Kabi

European Manufacturing

Integrated European supply chain supporting global customers
Reliable and secure supply
Production based in Italy for API and Portugal for FDF

Manufacturing Capabilities

Sterile beta-lactam APIs
Oral beta-lactam APIs
Lyophilized manufacturing
Crystallized sterile penicillins

Quality & Compliance

US FDA approved
EDQM approved
Additional major international regulatory approvals

Commercial & CDMO Solutions

Commercial API portfolio
Custom development projects
Process optimization support
End-to-end European manufacturing solutions

Our Beta-Lactam API Portfolio

Sterile Penicillins

Amoxicillin Sodium
Ampicillin Sodium
Benzylpenicillin Benzathine Coated
Benzylpenicillin Potassium
Benzylpenicillin Potassium Buffered
Benzylpenicillin Sodium
Benzylpenicillin Sodium Buffered
Buffered Benzylpenicillin Benzathine Coated
Cloxacillin Sodium
Flucloxacillin Sodium
Nafcillin Sodium
Nafcillin Sodium Buffered
Oxacillin Sodium
Oxacillin Sodium Buffered

Sterile Cephalosporins

Cefepime Arginine Crystallized
Cefepime Hydrochloride
Ceftazidime Pentahydrate
Ceftazidime Pentahydrate Buffered
Ceftriaxone Sodium

Sterile Combinations

Ampicillin / Sulbactam Sodium (2:1)
Piperacillin Sodium / Tazobactam Sodium (8:1)
Piperacillin Sodium / Tazobactam Sodium (8:1) EDTA and Sodium Citrate

ß-Lactamase Inhibitor

Sulbactam Sodium

Oral Penicillins

Ampicillin Anhydrous
Bacampicillin Hydrochloride
Cloxacillin Sodium
Dicloxacillin Sodium
Flucloxacillin Sodium
Mecillinam
Nafcillin Acid
Piperacillin Monohydrate
Pivmecillinam Hydrochloride

Veterinary products

Ampicillin Sodium Sterile
Ampicillin Trihydrate Sterile
Cloxacillin Benzathine Sterile
Cloxacillin Sodium
Cloxacillin Sodium Sterile
Hetacillin Potassium Sterile
Oxacillin Sodium Sterile

Tailored CDMO Solutions

Looking for a molecule not included in our commercial portfolio?

Our development and manufacturing teams support customers with tailored beta-lactam projects, from feasibility assessment and process development to manufacturing and regulatory support.

Capabilities

Custom API development
Process optimization
Technology transfer support
Sterile micronization
Bulk freeze-drying
Physical mixing in sterile environment
End-to-end manufacturing solutions