Fresenius Kabi builds on its broad range of expertise in flexible container technologies for infusion and clinical nutrition therapy.
As the originator of many container technologies that include the IV bag platform freeflex®, we wish to highlight the characteristics and advantages we offer to our partners to fill & finish their products in our PVC-free bags.
IV bags are widely used in hospitals and healthcare clinics all over the world. Plastic is preferred over glass as a packaging material for many types of pharmaceutical dosage forms due to its unbreakable, lightweight and leak-resistant characteristics. Furthermore, plastic containers are chemically inert and corrosion-resistant. They are additionally collapsible and can be easily molded or remolded.
Fresenius Kabi’s IV bag technology is the freeflex® container system. These IV bags are made of polyolefine, an inert plastic material consisting of polypropylene (PP) and thermoplastic elastomer, free of PVC and latex. freeflex® bags are approved for various infusion solutions and are compatible with more than 140 drugs based on internal Fresenius Kabi’s studies and published data based on containers with comparable polyolefine materials.
freeflex® are available as single- and multi-chamber bags in the size range of 50-1000 mL with one or more separate ship shape ports made of PP. Their arrow and color coding facilitate the easy identification of the injection and infusion ports, and tamperevident flip-off covers protect them from external contamination.
Tests have shown the infusion port to be compatible with all IV sets commonly available in the market. The container concept of freeflex® offers a strictly closed system for drug reconstitution to guarantee maximum sterility while ensuring intuitive and safe handling. 8-10
The package concept of freeflex® bags consists of a primary bag to hold the solution and a secondary bag as physical sterile protection. The secondary PVC-free film is clear and flexible; it protects the primary bag mechanically and against water loss through vaporing. The overwrap is easy to open and has excellent clarity to allow visual inspection. freeflex® bags are sterilized in their overwraps at 121°C.
Leading independent hospital physicians and pharmacists in France have awarded freeflex® the top accolade for innovation. It is representing Fresenius Kabi’s solution to the increasing complexity of drug handling and infusion protocols.
It is designed to simplify user handling and maximize patient safety. From the crystal-clear, non-PVC, phthalate-free bag and patented leak-resistant technology to the easy-to-handle bag design, every element of this innovative
and flexible container system makes freeflex® the perfect choice for safe infusions.
freeflex® bags are produced by Fresenius Kabi in many facilities around the world, including Fresenius Kabi Norge AS in Halden, which, as described below, is a competence center for the filling of IV drugs in bags based on decades of experience and state-of-the-art technologies.